Spotlight on Racial and Ethnic Disparities in Cardiovascular Disease
August 25, 2021
JOURNAL OF THE AMERICAN HEART ASSOCIATION
Cardiovascular diseases (CVD), principally ischemic heart disease and stroke, are the leading cause of death in the United States. Although management of CVD has led to improved mortality over the years, striking disparities in outcomes have persisted and widened among racial and ethnic groups. These disparities segregate along the lines of race and ethnicity, socioeconomic status, and geography. Health disparities, as defined by the World Health Organization, are “systematic, socially produced (and therefore modifiable) and unfair” conditions that dis...
Geographic and Socioeconomic Disparities in Major Lower Extremity Amputation Rates in Metropolitan Areas
August 25, 2021
JOURNAL OF THE AMERICAN HEART ASSOCIATION
Background: Rates of major lower extremity amputation in patients with peripheral artery disease are higher in rural communities with markers of low socioeconomic status, but most Americans live in metropolitan areas. Whether amputation rates vary within US metropolitan areas is unclear, as are characteristics of high amputation rate urban communities.
FDA Approves Expanded Peripheral Artery Disease (PAD) Indication for XARELTO® (rivaroxaban) Plus Aspirin to Include Patients After Lower-Extremity Revascularization (LER) Due to Symptomatic P
August 24, 2021
CISION PR NEWSWIRE
XARELTO® is the only anticoagulant in 20 years to show significant benefit in patients with PAD who remain at high risk for major thrombotic events, including acute limb ischemia and amputation. PAD impacts 20 million Americans and is the leading cause of amputations in the U.S., with rates continuing to rise.
Exercise, Medication and Diet Changes Key to Treating High Cholesterol
August 24, 2021
THE ROLLA DAILY NEWS
High levels of lipids (fats) in the blood, including cholesterol and triglycerides, is also called "hyperlipidemia."
Hyperlipidemia can lead to your blood vessels getting blocked with fatty deposits, limiting blood flow. This condition also increases your risk of developing cardiovascular disease, affecting blood vessels supplying the heart (coronary artery disease), brain (cerebrovascular disease) and arms and legs (peripheral artery disease).
Creation of a vascular inducing device using mesenchymal stem cells to induce angiogenesis
July 26, 2021
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
Abstract: Conventional treatments of peripheral vascular disease and coronary artery disease have partial success but are still limited. Methods to deliver angiogenic factors into ischemic areas using gene, protein and cell therapies are faced with difficult issues such a delivery, effective concentration and duration of action. Tissue engineering offers the possibility of creating a functional self-contained three-dimensional (3D) unit that works as a coordinated biological pump that can secrete a whole range of angiogenic factors. We report a tissue e...
Influence of pedal arch quality on 5-year survival and limb salvage in patients with diabetic foot ulcers undergoing peripheral angiography
July 13, 2021
VASCULAR
Introduction: The aim of this study was to evaluate the influence of pedal arch quality on 5-year survival and limb salvage in diabetic patients with foot wounds undergoing peripheral angiography.
First report of intravascular ultrasound-guided intravascular lithotripsy to treat an underexpanded stent in the superficial femoral artery
July 13, 2021
VASCULAR
Background/objective: To evaluate the safety and utility of a new in Europe intravascular ultrasound (IVUS) catheter in a case of peripheral arterial disease caused by in-stent restenosis of the superficial femoral artery.
Inflammation and its associations with aortic stiffness, coronary artery disease and peripheral artery disease in different ethnic groups: The HELIUS Study
July 7, 2021
EClinicalMedicine
Background: Evidence shows important ethnic differences in vascular dysfunction rates; however, the mechanisms driving these differences remain unclear. One potential factor is the ethnic differences in the role of inflammation in vascular injury. We tested the hypothesis that low-grade inflammation is unequally associated with vascular dysfunction in different ethnic groups.
Peripheral Artery Disease and Abdominal Aortic Aneurysm: The Forgotten Diseases in COVID-19 Pandemic. Results from an Observational Study on Real-World Management
July 6, 2021
DOCWIRE NEWS
It is well established that patients with peripheral artery disease (PAD) as well abdominal aortic aneurysm (AAA) have an increased cardiovascular (CV) mortality. Despite this higher risk, PAD and AAA patients are often suboptimality treated. This study assessed the CV profile of PAD and AAA patients, quantifying the survival benefits of target-based risk-factors modification even in light of the COVID-19 pandemic.
Can HbA1c Variability Predict Diabetic Complications?
July 6, 2021
DIABETES IN CONTROL
A study was conducted to assess if HbA1c variability impacts the incidence of diabetic complications, all-cause and cardiovascular mortality.
Increased variability in HbA1c has been associated with higher rates of diabetic complications and mortality. These significant fluctuations in HbA1c may increase mortality risk, especially in higher-risk populations such as geriatric patients. It is also unknown whether periods of hypoglycemia have negative impacts on organ function.
